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Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mmHg is greater at higher blood pressures, so that even modest reductions of severe hypertension can provide substantial benefit.
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In the general black population (without CKD), including those with diabetes, initial antihypertensive treatment should consist of a thiazide-type diuretic or a calcium channel blocker instead of an ACEI or ARB.
The patient is a 34-year-old African-American man who presented with a 4 week history of progressively worsening shortness of breath, cough associated with mucoid sputum, moderate epigastric pain, loose watery diarrhea and a weight loss of 30 lbs during this period.
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Irbesartan and hydrochlorothiazide tablets, USP are a combination of an angiotensin II receptor antagonist (AT 1 subtype), irbesartan, and a thiazide diuretic, hydrochlorothiazide (HCTZ).
If it is close to your next dose, do not take the missed dose.
Vasotec, in Vaseretic); hydrochlorothiazide (HCTZ, Microzide, Oretic); angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril (Capoten), fosinopril (Monopril), lisinopril (in Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); sulfa drugs; any other medications; or any of the ingredients in enalapril and hydrochlorothiazide tablets.
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Management of hypertension with the fixed combination of perindopril and amlodipine in daily clinical practice: results from the STRONG prospective, observational, multicenter study".
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The results of a very large clinical trial designed to give a definitive answer to the decades-old question of which of four commonly used families of high blood pressure medications should be prescribed first was published in the December 18, 2002 issue of the Journal of the American Medical Association.
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