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Un medicamento similar al gemfibrozil ha provocado cáncer, enfermedad de la vesícula biliar y dolores abdominales que culminaron en una apendicectomía.
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Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats.
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Two comparable trials studied the effects of colchicine in 204 participants with recurrent pericarditis and two trials studied 360 people with acute pericarditis.
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In addition to being reserved to more resistant cases, the increased incidence of recurrence observed in patients on glucorticoid therapy has been linked to the potentiation of virally induced pericarditis by steroids.
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Information for healthcare professionals: New safety information for colchicine (marketed as Colcrys).
Se miran de 10 a 15 núcleos porque puede haber muchos falsos positivos debido a que le hemos añadido mitógenos (de manera que las células se dividen de forma rápida y precipitada) y colchicina, los cuales pueden provocar mutaciones e irregularidades en los cromosomas.
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Medications should be assessed to identify those that may aggravate the patient's condition (e.
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All patients who discontinued therapy were followed up for recurrences and were included in all analyses.
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among non-oral medication however varied across therapeutic courses. Generic drug prices also increased over time, particularly after 2010, following the implementation of the Patient Protection and Reasonably priced Care Act (ACA) and the Generic Drug Person Price Amendments. The authors concluded that generic drug markets within the United States typically involve small-revenue merchandise and are increasingly tending toward duopoly or monopoly supply. Taken together, these findings recommend that the conventional wisdom involving generic medicine within the United States—that competitors among generic producers, facilitated by shopping for power consolidation among insurers and different purchasers, ends in increasing access to secure and efficient therapies for chronic illness, offsetting not less than to some extent the upper prices of newly launched and current branded medicine ( Aitken et al., 2016 ; Duggan et al., 2008 )—could also be less true now than earlier research prompt.
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