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We thank the trial participants and the clinical, administrative, and laboratory staff members at all sites; the members of the data and safety monitoring committee (Diederik van de Beek, Academic Medical Center, Amsterdam; Janet Derbyshire, University College London, London; Ronald Geskus, Academic Medical Center, Amsterdam; Andrew Kambugu, Makerere University, Kampala, Uganda; and David Mabey, London School of Hygiene and Tropical Medicine, London); and the independent members of the trial steering committee (David Cooper, University of New South Wales, Sydney; Robin Bailey, London School of Hygiene and Tropical Medicine, London; Robin Grant, University of Edinburgh, Edinburgh; and Jimmy Whitworth, London School of Hygiene and Tropical Medicine, London) for their advice and support.
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Thirteen patients were withdrawn for other reasons: four were accidentally not treated for four days (two in each group; all four received the assigned study medication the first day or the first two days), one patient in the placebo group withdrew consent, and eight had clinical deterioration and were treated with corticosteroids (two in the dexamethasone group and six in the placebo group).
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