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Our goal was to determine if striatal enlargements are similar in both SCHZ and SIP.

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Clozapine is the only antipsychotic medication that has been shown to be more effective than other antipsychotics in controlling psychotic symptoms.

It has not been FDA-approved for use as monotherapy in unipolar depression.

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The following efficacy variables were used to evaluate the efficacy of ziprasidone: PANSS total score (the sum of all 30 items); the PANSS negative subscale score (the sum of the seven negative items on PANSS); the CGI-severity (CGI-S) score, ranging from 1 (normal) to 7 (most severely ill) (), and the CGI-I score.

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Mixed Models for Repeated Measures using Categorical time Effects (MMRM).

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The evidence for the effectiveness of early interventions to psychosis appeared inconclusive.

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Psychosocial treatments are currently oriented according to the recovery model.

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Background: Tardive dyskinesia (TD) is a neurological condition characterized by involuntary movements of the orofacial region, limbs and trunk for which no definitive treatments have been established.

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Notably, these three connectivity-defined subgroups show significant differences in negative symptoms, indicating that the model-based physiological partitioning relates to clinical symptomatology.

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Psychoeducation can improve knowledge about illness, but there are equivocal findings that it increases treatment adherence unless there are also motivational enhancement and behavioural strategies for taking medication as prescribed.

Patients with obsessive-compulsive personality disorder have idealized standards often rewarded by others, whereas patients with OCD experience significant distress due to true obsessions and compulsions.

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Cardiac medications such as antiarrhythmic drugs are known to prolong ventricular repolarization and result in QT interval prolongation.

Methods: We investigate 39 individuals at ultra-high risk of psychotic disorder.

No laboratory test result is diagnostic for NMS.

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Background: Previous studies indicate that abnormal interaction of attention and emotion is implicated in the negative symptoms of schizophrenia (Strauss et al.

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Table 2 enumerates the incidence, rounded to the nearest percent, of treatment-emergent adverse reactions that occurred during acute therapy (up to 3 weeks) in patients with bipolar mania, including only those reactions that occurred in 2% or more of patients treated with ziprasidone and for which the incidence in patients treated with ziprasidone was greater than the incidence in placebo-treated patients.

Results: The sample was composed of 66% males, mean age of 35.

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In both models, neurocognition and negative symptoms were directly related to baseline, but not outcome, social and role functioning.

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Drake RE, Gates C, Whitaker A, Cotton PG.

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Discontinuations because of insufficient clinical response and adverse events were recorded.

In the second (follow-up) analyses we included 108 patients followed up-to 10 years from index admission.

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The disturbance causes clinically significant distress or impairment in social or occupational areas of functioning, or it impairs the person's ability to pursue some necessary task.

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Methods: The ToM performance of 23 females with SZ was compared to that of 25 females with BPD using independent samples t-tests.

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However, for most patients, the onset of mania in people older than 50 years should lead to an investigation for medical or neurologic disorders, such as cerebrovascular disease.

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Institutional review board approval was obtained at each site, and all participants provided written informed consent.

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We used generalized estimating equation based-regression models to examine group differences using age, sex and grey matter proportion within the voxel as covariates (SAS PROC GENMOD).

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Presence of significant cardiac disease, including uncompensated congestive heart failure, myocardial infarction within the past 6 months or known history of congenital long QT syndrome.

For example, cannabis use has been shown to be associated with an earlier onset of psychosis and to correlate, in a bidirectional way, with an adverse course of psychotic symptoms in persons with schizophrenia.

Such findings have important implications to the etiology of abnormalities in goal-oriented behavior in schizophrenia.

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However, existing treatments are complex and usually consist of practice on multiple exercises and application of many different strategies and thus the active ingredients of these interventions remain unknown.

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