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I am so thankful for Gleevec! I did have some side-effects but prior to Gleevec, taking interferon and hydroxyurea led to much more severe side effects. I had aching limbs, and I now have a skin reddening/rash--like rosacea on my cheeks and my upper arms are reddish--like a mild sunburn. I have tummy issues now--gurgling, diarrhea, cramping, etc., but they are easily managed with imodium. Gleevec has extended my survival and I had the honor of meeting Dr Druker who developed the drug, at Oregon Health and Science University. He was absolutely wonderful as was the care I received there.
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I have been on Gleevec since 2/2006. My white blood cell count went from 350,000 to 75,000 in less then three months. I went into full moleculer remission by 2/2007. Have the BCR-ABL blood test every 6 months and there is no more Philadelphia Chromosome since. I still can get nauseated and once in a while vomit if I do not take my Reglan correctly or take Zofran with it, but that's a minor annoyance since this medicine saved my life. I would have only had a 40% chance of survival if I would have had a bone marrow transplant. This medicine is a 95% chance of survival and I'm just about to that magical mark of 10 years on the medicine.

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