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It is important to note that this review focuses on myocardial substrate metabolism in HF, and not on the well-documented HF-induced abnormalities in the transfer of energy from mitochondrial ATP to systolic and diastolic work.
However, a recent randomized trial, comparing an initial diagnostic strategy of exercise nuclear myocardial perfusion imaging (MPI) with standard exercise treadmill testing, in symptomatic women with suspected CAD and preserved functional capacity who were able to exercise, did not show an incremental benefit of the more expensive MPI strategy on clinical outcomes.
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Treatment for patients with stable coronary artery disease is medical therapy and lifestyle modification.
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Despite the clear beneficial effects of angiotensin converting enzyme inhibitors and angiotensin receptor antagonists in slowing the progression of HF, there are little data on the metabolic consequences of suppression of the effects of angiotensin in HF.
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In African countries south of the Sahara Desert, new HIV infections have fallen by 48 percent since 2000.
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Heart disease risk is also higher among Mexican Americans, American Indians, native Hawaiians, and some Asian Americans.
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