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The complexes internalized into endosomes and Dig-siRNAs separated from bsAbs, but Dig-siRNA was not released into the cytoplasm; bsAb-targeting alone was thus not sufficient for effective mRNA knockdown.
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The social, economic and human effects of this disease are dramatic: 40% of the world's population is currently at risk for malaria, and it kills an African child every 30 seconds(7).
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This result was confirmed in further assays on a different occasion (data not shown).
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Kuschner R, Heppner D, Andersen S, Wellde B, Hall T, Schneider I, Ballou W, Foulds G, Sadoff J, Schuster B: Azithromycin prophylaxis against a chloroquine resistant strain of Plasmodium falciparum.
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They added that increased APP immunoreactivity was also reported in retinal cells of old aged persons, in retinitis pigmentosa and in age-related macular degeneration.
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AGOA provides incentives for African countries to improve their investment climates, reduce corruption, respect human and labor rights and the rule of law, improve infrastructure and harmonize trade standards to help them become more competitive in the global marketplace.
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All 135 resistant cases determined by the in vivo test were also resistant by the in vitro test; and all 40 sensitive cases determined by the in vitro test also proved to be sensitive by the in vivo test.
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