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Gregory RE, Ettinger DS (1998) 5-HT3 receptor antagonists for the prevention of chemotherapy-induced nausea and vomiting.

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It has also been shown to produce analgesic effects, most probably acting as a partial agonist at the μ-opioid receptor.

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With the use of a block-balanced randomization list (12 patients per block), patients were randomly assigned to receive one of three antiemetic treatments in a blinded fashion in the first 24 hours after the administration of chemotherapy.

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