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I have had Polycythemia vera for 25 years. I was started on hydroxyurea two months ago and recently developed severe petechial hemorrhaging. I was admitted to the hospital with a platelet count of 9,000. I received a six pack of platelets and over seven days (being off the medication) my platelet count had climbed to 74,000. As of Sunday, July 5th, it was at 139,000 (off the medication for ten days). I was given the medication to help prevent the POTENTIAL of developing a blood clot. I have managed my Polycythemia vera pretty well without medication for 25 years (I do take baby aspirin) and wish I had never taken this.
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Advise patients about drugs that are cross-reactive and about drugs that must be avoided.

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Subjects who consented to participate in the study may have been eager to benefit from the possibility of improvement that could be brought in by HU therapy; they received regular attention and clinical center staff support that may not be available to all patients with SCA.

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About 10 minutes into the infusion, the nurse becomes concerned that he is having an anaphylactic reaction to the drug because he is experiencing: A) Dyspnea B) Bradycardia C) Hypertension D) Increased body temperature 10.

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Hydroxyurea no va a curar la anemia de células falciformes.

The National Institutes of Health has sponsored two Phase III randomized, placebo-controlled trials, initially in adults, and subsequently in children with sickle cell anemia (SCA).

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Measurements of the oxygen level in the patient's arterial blood, of the concentration of vitamin B 12 in the blood serum, and of leukocyte alkaline phosphatase (LAP) staining can be used to distinguish PV from certain types of leukemia or from other types of polycythemia.

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While a few patients with PV may have a red cell mass level within the normal range if they have had recent heavy bleeding, a high score may eliminate the need for some other tests.

William Dameshek, placed ET within a family of blood diseases called myeloproliferative disorders.

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Forty-eight-year-old Ayoola Olajide is living well with sickle cell anaemia (SS).

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Their modular nature makes these networks ideal tools for the analysis of large association studies like the work on genotype-phenotype associations in sickle cell disease.

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If contact with crushed or opened capsules occurs on the eye(s), the affected area should be flushed thoroughly with water or isotonic eyewash designated for that purpose for at least 15 minutes.

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Before the sudden rise in white blood cells, symptoms of the disease are rare and for this reason it is often diagnosed by chance, as such it is a chronic disorder, gradual and slow in its evolution process, the disease does not produce many significant symptoms through which it might otherwise be easily detected.

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Stimulating fetal hemoglobin by increasing gamma-globin synthesis in patients with sickle cell disease would be expected, if the production of sickle hemoglobin is decreased concomitantly, to reduce the formation of intracellular S polymer and improve the acute and chronic hemolytic and vasoocclusive complications of the disease.

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