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At 12 months, 24 patients (13%) in the colchicine group and 60 patients (33%) in the control group had a first recurrence.

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The commonest causes of recurrences are idiopathic, viral, autoimmune (usually related to a connective tissue disease or a pericardial injury syndrome), inadequate medical treatment of either the index attack or the recurrence, and less commonly, a neoplastic origin.

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La colchicina pertenece a una clase de medicamentos llamados agentes contra la gota.

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Because colchicine is a substrate for both the CYP3A4 metabolizing enzyme and the P-glycoprotein efflux transporter, inhibition of either of these pathways may lead to colchicine-related toxicity.

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My blood tests showed low uric acid content so iot looks like I have not got gout.

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The specific goals of this research are to better understand how urate crystals activate white blood cells called neutrophils, leading to acute gout attacks; how urate crystals affect the immune system, leading to chronic gout; and how urate crystals interact with bone cells in a way that causes debilitating bone lesions among people with chronic gout.

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