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Standard therapy includes rituximab, an anti-CD20 monoclonal antibody, either alone or in combination with purine nucleoside analogs such as fludarabine or 2-chlorodeoxyadenosine, alkylating agents (with or without steroids), or combination chemotherapy.
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The frequency of adverse effects for the 385 eligible women who received at least one course of treatment is shown in Table 3 Occurrence of Adverse Effects According to Severity and Treatment Group.
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ALDHs protect these actively proliferating tissues against toxic effects of phosphoramide mustard and by converting to that does not give rise to the toxic metabolites phosphoramide mustard and acrolein.
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