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For me Allopurinol is a lifesaver! I have been using the pills for about the past 15 years. I am now 76. Since I remember myself I've been leading an active way of life, I do exercises and go in for sports. With such lifestyle gout attacks make my life stop. That's why allopurinol pills naturally bring me back alive and I have never had any side effects from them.

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About 12 years ago my doctor found out that the level of uric acid in my blood was above normal. Soon afterwards I started having gout attacks and felt myself an old helpless ass. But my doc, a nice young lady, prescribed me with Allopurinol. It has been 10 years since I started taking the pills and I'm still damn grateful to my wonderful doctor!

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It is used to treat high uric acid levels in the blood or urine caused by certain types of cancer chemotherapy.

When different scales were used to measure the same conceptual domain, we planned to calculate the standardised mean differences (SMD) with corresponding 95% CIs instead.

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This summary of a Cochrane review presents what we know from research about the effect of allopurinol compared with placebo or other treatments that reduce uric acid levels in treating people with chronic gout.

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Secondgeneration antihistamines, such as cetirizine and fexofenadine, have been considered, but have not proven efficacious.

Rarely, a patient may develop varying degrees of bone marrow depression, affecting one or more cell lines, while receiving Allopurinol alone.

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Single studies reported no difference in pain reduction when allopurinol 300 mg daily was compared with placebo over 10 days, and no difference in tophus regression when allopurinol 200 to 300 mg daily was compared with febuxostat 80 mg daily.

With the simultaneous administration of this drug and azathioprine or mercaptopurine it is observed accumulation of the latter in the body, because in connection with the activity of xanthine oxidase inhibition with allopurinol necessary to biotransformation of drugs, slowing their metabolism and elimination.

However, there is no need for complacency and the English Pharmacy Board EPB must build on its successful leadership work to ensure that pharmacists are supported in delivering effective patient care.

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We will review titles and abstracts and if more information is required to determine whether a trial meets the inclusion criteria, we will obtain the full text.

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Allopurinol and its primary active metabolite, oxipurinol, are eliminated by the kidneys; therefore, changes in renal function have a profound effect on dosage.

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The FDA dosing guide lists 200 to 300 mg daily as typical doses for people with mild gout and doses of 400 to 600 mg daily for people with moderately severe tophaceous gout.

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